DETOXIFICATION

OPIATES
What is an Opioid?

Opioids are drugs that are either derived from opiates (drugs created directly form opium, such as morphine or codeine) or are chemically related to opiates or opium. Examples of opioids include some prescription painkillers (such as oxycodone, hydrocodone, buprenorphine, methadone, and heroin).

Is Opioid Dependence a Medical Condition?
Opioids, such as some prescription pain medications or heroin, attach to opioid receptors in the brain, which stimulate the release of dopamine and produce pleasurable feelings. When the opioid eventually detaches from the receptors, people experience withdrawal and cravings and have a strong need to repeat the experience. Drug use often begins as a choice, but frequent use can cause the brain cells to change the way they work. The brain is "re-set" to think that the drug is necessary for survival. Researchers have discovered that many drugs, including opioids, cause long-term changes in the brain. These changes can cause people to have cravings years after they stop taking drugs.

What is SUBOXONE™?
SUBOXONE™™ is the first opioid medication approved under DATA 2000 for the treatment of opioid dependence in a private office setting.

How does SUBOXONE™ benefit you?
SUBOXONE™ can decrease cravings and relieve withdrawal symptoms. This can help you remain in treatment and gain control over your dependence without the distraction of cravings and fear of withdrawal.

SUBOXONE™ offers a way to treat opioid dependence- in a doctor's office--- with privacy, confidentiality, and safety. People treated with SUBOXONE™ generally don't need to be hospitalized, make daily visits to a clinic, or go away from home for residential treatment. As a result, treatment with SUBOXONE™ may allow more time for work, family and other activities.

How effective is SUBOXONE™?
Buprenorphine, the primary active ingredient in SUBOXONE™, has been studied extensively since 1978, when it was first proposed for the treatment of opioid dependence.

A number of clinical trials have established that buprenorphine is effective for:

SUBOXONE™, together with counseling, can help you remain in treatment. By having your withdrawal symptoms and cravings better controlled, your overall treatment can focus on resolving issues and gaining skills to avoid triggers---- situations or stimuli that may cause you to RELAPSE. You can also work with your physician to address issues that may have been contributing to your use of opioids, such as depression, anxiety, or other psychiatric conditions.

Can I Switch form Methadone to SUBOXONE™?
It is possible to switch to SUBOXONE™ from methadone treatment. Everyone's situation is different, so talk to your doctor first to se if switching is right for you.

For more information please visit www.SUBOXONE.com.